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Journal Article

Distribution of GABAA receptor subunit mRNAs in rat lumbar spinal cord

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Seeburg,  Peter H.
Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society;

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Citation

Wisden, W., Gundlach, A. L., Barnard, E. A., Seeburg, P. H., & Hunt, S. P. (1991). Distribution of GABAA receptor subunit mRNAs in rat lumbar spinal cord. Molecular Brain Research, 10(2), 179-183. doi:10.1016/0169-328X(91)90109-B.


Cite as: https://hdl.handle.net/21.11116/0000-0000-6E07-E
Abstract
The expression of various GABAA receptor subunit mRNAs (alpha 1, alpha 2, alpha 3, alpha 5, beta 1, beta 2, beta 3, gamma 2, delta) was studied in the adult rat lumbar spinal cord by in situ hybridization. Of these, only alpha 2, alpha 3, beta 3 and gamma 2 mRNAs are expressed at significant levels. The alpha 3, beta 3 and gamma 2 transcripts are present in many neurons throughout the Rexed laminae, whereas the alpha 2 mRNA is restricted to motor neurons and adjacent cells.