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Meeting Abstract

Indirekter Nachweis von Laktat in vivo mittels Chemical Exchange Saturation Transfer

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Zaiss,  M
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Bauer, C., Meissner, J.-E., Korzowski, A., Zaiss, M., Ladd, M., & Bachert, P. (2016). Indirekter Nachweis von Laktat in vivo mittels Chemical Exchange Saturation Transfer. In 47. Jahrestagung der Deutschen Gesellschaft für Medizinische Physik (DGMP 2016) / 19. Jahrestagung der Deutschen Sektion der International Society for Magnetic Resonance in Medicine (ISMRM-DS 2016) (pp. 41-42).


Cite as: http://hdl.handle.net/21.11116/0000-0000-7C6F-A
Abstract
Using Chemical Exchange Saturation Transfer (CEST)-MR Imaging, an increased magnetisation transfer in the frequency domain of lactate effect could be observed in the human calf after muscular strain. Employing 31P-spectroscopy, it could additionally be shown that the measured effect cannot be solely explained by a change in pH value. In conclusion it is possible to detect an intra-cellular change in lactate concentration in vivo.