Improvement of Quantification of 1H Cardiac MR Spectra Acquired at 3T by the 
Use of Prior Knowledge

Fillmer, A; Hock, A; Henning, A

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Improvement of Quantification of 1H Cardiac MR Spectra Acquired at 3T by the Use of Prior Knowledge

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Henning, A
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Fillmer, A., Hock, A., & Henning, A. (2016). Improvement of Quantification of 1H Cardiac MR Spectra Acquired at 3T by the Use of Prior Knowledge. In 24th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2016).

Cite as: https://hdl.handle.net/21.11116/0000-0000-7CC8-4

Abstract

1H cardiac MRS is a promising tool for investigation of human heart disease. In this context the independent quantification of intramyocellular (IMCL) and extramyocellular lipids (EMCL) is desired. Quantification itself, however, remains challenging. This work investigates, whether quantification of metabolite signals within 1H cardiac MR spectra could be improved by the use of prior knowledge about the behavior of metabolite signals in the quantification process.