Sequence and expression of human GABAA receptor α1 and β1 subunits

Schofield, Peter R.; Pritchett, Dolan B.; Sontheimer, Harald; Kettenmann, Helmut; Seeburg, Peter H.

doi:10.1016/0014-5793(89)80563-0

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Sequence and expression of human GABAA receptor α1 and β1 subunits

MPS-Authors

/persons/resource/persons95292

Seeburg, Peter H.
Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society;

External Resource

http://onlinelibrary.wiley.com/doi/10.1016/0014-5793(89)80563-0/epdf
(Any fulltext)

https://doi.org/10.1016/0014-5793(89)80563-0
(Any fulltext)

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Schofield, P. R., Pritchett, D. B., Sontheimer, H., Kettenmann, H., & Seeburg, P. H. (1989). Sequence and expression of human GABAA receptor α1 and β1 subunits. FEBS Letters, 244(2), 361-364. doi:10.1016/0014-5793(89)80563-0.

Cite as: https://hdl.handle.net/21.11116/0000-0000-8D23-A

Abstract

The deduced amino acid sequences of cDNA clones encoding human GABAA receptor α1 and β1 subunits are presented. The human subunits display very high levels of sequence identity with the corresponding bovine receptor subunits. The cloned human GABAA receptor subunits induce the formation of GABA-gated chloride channels when expressed in mammalian cells.