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Dynamic Functional Connectivity in Event-Related fMRI and its implications in Epilepsy

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Erb,  M
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  K
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Sahib, A., Erb, M., Scheffler, K., Ethofer, T., & Focke, N. (2017). Dynamic Functional Connectivity in Event-Related fMRI and its implications in Epilepsy. Poster presented at 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA.


Cite as: http://hdl.handle.net/21.11116/0000-0000-C48D-4
Abstract
To assess the impact of repetition time (TR) and window size on the temporal features of BOLD functional connectivity (FC) using a sliding window approach in event-related fMRI. in addition, test the feasibility of this approach in epilepsy. We calculated the functional connectivity degree (FCD) by counting the total number of connections of a given voxel above a predefined threshold based on Pearson correlation. In summary, we showed that dynamic FCD transients are better detectable with sub-second TR than conventional TR, indicating a potential to study the temporal characteristics of interictal epileptiform discharges and seizures in epilepsy patients.