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High resolution maps of individual macromolecule components in the human brain at 9.4T

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Nassirpour,  S
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons192839

Chang,  P
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84402

Henning,  A
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Nassirpour, S., Chang, P., & Henning, A. (2017). High resolution maps of individual macromolecule components in the human brain at 9.4T. In 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017) (pp. 619-619).


Cite as: https://hdl.handle.net/21.11116/0000-0000-C59E-0
Abstract
Although ultra-short TE spectroscopy sequences enhance the information content of the spectrum, they are, in their nature, prone to quantification biases if the macromolecular (MM) components are not taken into account The aim of this study, was to 1) perform macromolecule mapping at 9.4T using an ultra-short TE double-inversion recovery (DIR) MRSI sequence, 2) model and parametrize the individual MM components, and 3) extract high resolution maps of individual MM components using the modelled MM basis set.