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Dynamic resting state fMRI in mice: detection of Quasi-Periodic Patterns

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Keliris,  G
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Belloy, M., Naeyaert, M., Keliris, G., Abbas, A., Keilholz, S., van der Linden, A., et al. (2017). Dynamic resting state fMRI in mice: detection of Quasi-Periodic Patterns. In 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017) (pp. 566-567).


Cite as: https://hdl.handle.net/21.11116/0000-0000-C5AC-0
Abstract
We report, to our knowledge, the first application of a dynamic rsfMRI approach in mice and show the reliable detection of Quasi-Periodic Patterns (QPP) at both the group-level as well as in single-subject data. These patterns are consistent with QPPs detected previously in humans and rats, displaying a high intensity wave spreading across the cortex from lateral towards upward medial, followed by a low intensity wave in the same direction. These findings are promising for the application of QPPs towards investigating mouse resting state functional connectivity and its development as a potential new pre-clinical tool.