In vivo and in vitro identification of Z-BOX C - a new bilirubin oxidation end 
product

Ritter, Marcel; Neupane, Sandesh; Seidel, Raphael A.; Steinbeck, Christoph; Pohnert, Georg

doi:10.1039/C8OB00164B

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In vivo and in vitro identification of Z-BOX C - a new bilirubin oxidation end product

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Citation

Ritter, M., Neupane, S., Seidel, R. A., Steinbeck, C., & Pohnert, G. (2018). In vivo and in vitro identification of Z-BOX C - a new bilirubin oxidation end product. Organic & Biomolecular Chemistry, 16(19), 3553-3555. doi:10.1039/C8OB00164B.

Cite as: https://hdl.handle.net/21.11116/0000-0000-B8B7-2

Abstract

A new bilirubin oxidation end product (BOX) was isolated and characterized. The formation of the so called Z-BOX C proceeds from bilirubin via propentdyopents as intermediates. It was detected in pathological human bile samples using liquid chromatography / mass spectrometry underlining its potential relevance for liver dysfunction and cerebral vasospasms.