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Potassium channels expressed from rat brain cDNA have delayed rectifier properties

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Sakmann,  Bert
Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society;

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Seeburg,  Peter H.
Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society;

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Citation

Stühmer, W., Stocker, M., Sakmann, B., Seeburg, P. H., Baumann, A., Grupe, A., et al. (1988). Potassium channels expressed from rat brain cDNA have delayed rectifier properties. FEBS Letters, 242(1), 199-206. doi:10.1016/0014-5793(88)81015-9.


Cite as: https://hdl.handle.net/21.11116/0000-0000-BAFF-0
Abstract
Injection into Xenopus oocytes of RNA synthesized in vitro using the rat brain cDNA RCK1 as a template or nuclear injection of the cDNA results in the expression of functional potassium channels. These channels exhibit properties similar to those of the non-inactivating delayed rectifier channel found in mammalian neurons and other excitable cells.