Strong selection during the last millennium for African ancestry in the admixed 
population of Madagascar

Pierron, Denis; Heiske, Margit; Razafindrazaka, Harilanto; Pereda-loth, Veronica; Sanchez, Jazmin; Alva, Omar; Arachiche, Amal; Boland, Anne; Olaso, Robert; Deleuze, Jean-Francois; Ricaut, Francois-Xavier; Rakotoarisoa, Jean-Aimé; Radimilahy, Chantal; Stoneking, Mark; Letellier, Thierry

doi:10.1038/s41467-018-03342-5

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Strong selection during the last millennium for African ancestry in the admixed population of Madagascar

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Stoneking, Mark
Human Population History, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society;

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Pierron_Strong_NatComm_2018.pdf
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引用

Pierron, D., Heiske, M., Razafindrazaka, H., Pereda-loth, V., Sanchez, J., Alva, O., Arachiche, A., Boland, A., Olaso, R., Deleuze, J.-F., Ricaut, F.-X., Rakotoarisoa, J.-A., Radimilahy, C., Stoneking, M., & Letellier, T. (2018). Strong selection during the last millennium for African ancestry in the admixed population of Madagascar. Nature Communications, 9:. doi:10.1038/s41467-018-03342-5.

引用: https://hdl.handle.net/21.11116/0000-0000-EC1A-A

要旨

The population of Madagascar arose from admixture of Austronesian and Bantu genetic backgrounds. Analyzing local ancestry in genomes of 700 Malagasy, Pierron et al. identify signals of recent positive selection for African ancestry in a region on chromosome 1 with implications for physiology and disease risk.