Steering cell migration by alternating blebs and actin-rich protrusions.

Diz-Muñoz, Alba; Romanczuk, Pawel; Yu, Weimiao; Bergert, Martin; Ivanovitch, Kenzo; Salbreux, Guillaume; Heisenberg, Carl-Philipp; Paluch, Ewa

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Steering cell migration by alternating blebs and actin-rich protrusions.

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Diz-Muñoz, A., Romanczuk, P., Yu, W., Bergert, M., Ivanovitch, K., Salbreux, G., et al. (2016). Steering cell migration by alternating blebs and actin-rich protrusions. BMC Biology, 14: 74.

Cite as: https://hdl.handle.net/21.11116/0000-0001-0377-6

Abstract

High directional persistence is often assumed to enhance the efficiency of chemotactic migration. Yet, cells in vivo usually display meandering trajectories with relatively low directional persistence, and the control and function of directional persistence during cell migration in three-dimensional environments are poorly understood.