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Journal Article

Liquid-liquid phase separation in biology.

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Hyman,  Anthony
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

Weber,  Christian
Max Planck Society;

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Citation

Hyman, A., Weber, C., & Jülicher, F. (2014). Liquid-liquid phase separation in biology. Annual Review of Cell and Developmental Biology, 30, 39-58.


Cite as: http://hdl.handle.net/21.11116/0000-0001-05A4-0
Abstract
Cells organize many of their biochemical reactions in non-membrane compartments. Recent evidence has shown that many of these compartments are liquids that form by phase separation from the cytoplasm. Here we discuss the basic physical concepts necessary to understand the consequences of liquid-like states for biological functions.