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A NOMPC-dependent membrane-microtubule connector is a candidate for the gating spring in fly mechanoreceptors.

MPS-Authors
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Liang,  Xin
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Madrid,  Johnson
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Verbavatz,  Jean-Marc
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Schiklenk,  Christoph
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Wilsch-Bräuninger,  Michaela
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Bogdanova,  Aliona
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Howard,  Jonathon
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Liang, X., Madrid, J., Gärtner, R., Verbavatz, J.-M., Schiklenk, C., Wilsch-Bräuninger, M., et al. (2013). A NOMPC-dependent membrane-microtubule connector is a candidate for the gating spring in fly mechanoreceptors. Current Biology: CB, 23(9), 755-763.


Cite as: https://hdl.handle.net/21.11116/0000-0001-0688-F
Abstract
Mechanoreceptors contain compliant elements, termed "gating springs," that transfer macroscopic stimuli impinging on the cells into microscopic stimuli that open the mechanosensitive channels. Evidence for gating springs comes from mechanical experiments; they have not been identified molecularly or ultrastructurally.