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Limiting amounts of centrosome material set centrosome size in C. elegans embryos.

MPS-Authors
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Decker,  Markus
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Jaensch,  Steffen
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Pozniakovsky,  Andrei I.
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Zinke,  Andrea
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

/persons/resource/persons78916

Zachariae,  Wolfgang
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Myers,  Eugene
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

/persons/resource/persons219253

Hyman,  Anthony A.
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Decker, M., Jaensch, S., Pozniakovsky, A. I., Zinke, A., O'Connell, K. F., Zachariae, W., et al. (2011). Limiting amounts of centrosome material set centrosome size in C. elegans embryos. Current Biology: CB, 21(15), 1259-1267.


Cite as: https://hdl.handle.net/21.11116/0000-0001-0A4A-2
Abstract
The ways in which cells set the size of intracellular structures is an important but largely unsolved problem [1]. Early embryonic divisions pose special problems in this regard. Many checkpoints common in somatic cells are missing from these divisions, which are characterized by rapid reductions in cell size and short cell cycles [2]. Embryonic cells must therefore possess simple and robust mechanisms that allow the size of many of their intracellular structures to rapidly scale with cell size.