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Journal Article

Turing's next steps: the mechanochemical basis of morphogenesis.

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Howard,  Jonathon
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Grill,  Stephan W.
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Bois,  Justin
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Howard, J., Grill, S. W., & Bois, J. (2011). Turing's next steps: the mechanochemical basis of morphogenesis. Nature Reviews. Molecular Cell Biology, 12(6), 400-406.


Cite as: https://hdl.handle.net/21.11116/0000-0001-0AE5-2
Abstract
Nearly 60 years ago, Alan Turing showed theoretically how two chemical species, termed morphogens, diffusing and reacting with each other can generate spatial patterns. Diffusion plays a crucial part in transporting chemical signals through space to establish the length scale of the pattern. When coupled to chemical reactions, mechanical processes - forces and flows generated by motor proteins - can also define length scales and provide a mechanochemical basis for morphogenesis.