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Automated tracking and analysis of centrosomes in early Caenorhabditis elegans embryos

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Jaensch,  Steffen
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Decker,  Markus
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Hyman,  Anthony A.
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Myers,  Eugene
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Jaensch, S., Decker, M., Hyman, A. A., & Myers, E. (2010). Automated tracking and analysis of centrosomes in early Caenorhabditis elegans embryos. Bioinformatics (Oxford, England), 26(12), 13-20.


Cite as: https://hdl.handle.net/21.11116/0000-0001-0B1D-4
Abstract
Motivation: The centrosome is a dynamic structure in animal cells that serves as a microtubule organizing center during mitosis and also regulates cell-cycle progression and sets polarity cues. Automated and reliable tracking of centrosomes is essential for genetic screens that study the process of centrosome assembly and maturation in the nematode Caenorhabditis elegans.