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Journal Article

Lipidomics: coming to grips with lipid diversity.

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Shevchenko,  Andrej
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Simons,  Kai
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Shevchenko, A., & Simons, K. (2010). Lipidomics: coming to grips with lipid diversity. Nature Reviews. Molecular Cell Biology, 11(8), 593-598.


Cite as: https://hdl.handle.net/21.11116/0000-0001-0BA4-A
Abstract
Although lipids are biomolecules with seemingly simple chemical structures, the molecular composition of the cellular lipidome is complex and, currently, poorly understood. The exact mechanisms of how compositional complexity affects cell homeostasis and its regulation also remain unclear. This emerging field is developing sensitive mass spectrometry technologies for the quantitative characterization of the lipidome. Here, we argue that lipidomics will become an essential tool kit in cell and developmental biology, molecular medicine and nutrition.