English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Journal Article

Spatial Regulators for Bacterial Cell Division Self-Organize into Surface Waves in Vitro

MPS-Authors
/persons/resource/persons219402

Loose,  Martin
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

/persons/resource/persons15815

Schwille,  Petra
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Loose, M., Fischer-Friedrich, E., Ries, J., Kruse, K., & Schwille, P. (2008). Spatial Regulators for Bacterial Cell Division Self-Organize into Surface Waves in Vitro. Science, 320(5877), 789-792.


Cite as: https://hdl.handle.net/21.11116/0000-0001-0E95-8
Abstract
In the bacterium Escherichia coli, the Min proteins oscillate between the cell poles to select the cell center as division site. This dynamic pattern has been proposed to arise by self-organization of these proteins, and several models have suggested a reaction-diffusion type mechanism. Here, we found that the Min proteins spontaneously formed planar surface waves on a flat membrane in vitro. The formation and maintenance of these patterns, which extended for hundreds of micrometers, required adenosine 5′-triphosphate (ATP), and they persisted for hours. We present a reaction-diffusion model of the MinD and MinE dynamics that accounts for our experimental observations and also captures the in vivo oscillations.