Temperature-induced size-control of bioactive surface patterns

Ionov, Leonid; Synytska, Alla; Diez, Stefan

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Temperature-induced size-control of bioactive surface patterns

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Ionov, Leonid
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Diez, Stefan
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Ionov, L., Synytska, A., & Diez, S. (2008). Temperature-induced size-control of bioactive surface patterns. Advanced Functional Materials, 18, 1501-1508.

Cite as: https://hdl.handle.net/21.11116/0000-0001-0EA6-5

Abstract

We present a novel method to produce bioactive surface patterns whose size can be changed in response to a variation of the environmental conditions, rather than local treatment. Our approach is based on the structured surface-immobilization of thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) polymer chains with different transition temperatures. We experimentally demonstrate how the size of an area in which a particular polymer is collapsed or swollen can be controlled by ambient temperature. We show the temperature-induced size-control of a bioactive surface pattern by embedding functional motor proteins into the switchable polymer layers