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Journal Article

Aberrant Receptor-Mediated Endocytosis of Schistosoma mansoni Glycoproteins on Host Lipoproteins

MPS-Authors
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Sprong,  Hein
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Suchanek,  Monika
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Thiele,  Christoph
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Sprong, H., Suchanek, M., Dijk, S. M. v., Remoortere, A. v., Klumperman, J., Avram, D., et al. (2006). Aberrant Receptor-Mediated Endocytosis of Schistosoma mansoni Glycoproteins on Host Lipoproteins. PLoS Medicine, 3(8), e253-0001-e253-0011.


Cite as: https://hdl.handle.net/21.11116/0000-0001-0FF7-9
Abstract
Bilharzia is one of the major infections affecting the public health and socioeconomics circumstances in (sub) tropical areas. Its causative agents are schistosomes. Since these worms remain in their host for decades, they have developed mechanisms to evade or resist the immune system. Like several other parasites, their surface membranes are coated with a protective layer of glycoproteins that are anchored by a lipid modification.