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Buildingbrains-3d: A tool to integrate neuron morphologies into 3d brain reconstructions

MPS-Authors
/persons/resource/persons84931

Egger,  Robert
Former Research Group Computational Neuroanatomy, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84910

Oberlaender,  Marcel
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Former Research Group Computational Neuroanatomy, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Johnson, A., Zhovnir, O., Egger, R., Sakmann, B., & Oberlaender, M. (2014). Buildingbrains-3d: A tool to integrate neuron morphologies into 3d brain reconstructions. Poster presented at 44th Annual Meeting of the Society for Neuroscience (Neuroscience 2014), Washington, DC, USA.


Cite as: https://hdl.handle.net/21.11116/0000-0001-3217-D
Abstract
BuildingBrains-3D (BB3D, buildingbrains-3d.org) is a scalable platform of web-based tools for assimilating and analyzing complete 3D reconstructions of individual neurons with respect to their precise 3D location in the brain. Presently these reconstructions are the basis for determining excitatory and inhibitory cell-types serving as sampling sets for large-scale dense connectivity simulations over macroscopic scales in the rat barrel cortex. BB3D is scalable, however, and provides a stable platform for Neuroscientists from laboratories around the world to integrate their reconstructions into common reference frames (e.g. rat cortex, see Egger et al.) to extract standardized morphological features and to obtain insights into the organizational principles of neural circuits within and across brains, regions and species.