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Functional ASL at 9.4 T: a comparison between balanced SSFP and GRE-EPI readout

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Bause,  Jonas
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Ehses,  P
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Shajan,  Gunamony
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  Klaus
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Pohmann,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Bause, J., Ehses, P., Shajan, G., Scheffler, K., & Pohmann, R. (2014). Functional ASL at 9.4 T: a comparison between balanced SSFP and GRE-EPI readout. Poster presented at Joint Annual Meeting ISMRM-ESMRMB 2014, Milano, Italy.


Cite as: http://hdl.handle.net/21.11116/0000-0001-32F8-F
Abstract
Functional ASL has a higher specificity and reproducibility than BOLD fMRI. However, the perfusion related signal is typically in the range of a few percent and the spatial and temporal resolution of arterial spin labeling imaging rather limited. ASL at ultra-high field can benefit from higher intrinsic SNR and increased longitudinal relaxation times. We investigated bSSFP and GRE-EPI as possible readout schemes for fASL studies at 9.4 T and were able to measure the first time stimulus evoked perfusion changes in the human motor cortex at this field strength.