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MaxSynBio - Avenues towards creating cells from the bottom up

MPS-Authors

Spatz,  J.
Max Planck Institute for Medical Research, Max Planck Society;

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Bodenschatz,  Eberhard
Laboratory for Fluid Dynamics, Pattern Formation and Biocomplexity, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

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Herminghaus,  Stephan
Grenzflächen, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Vidaković-Koch,  Tanja       
Process Systems Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society;

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Sundmacher,  Kai       
Process Systems Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society;

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引用

Schwille, P., Spatz, J., Landfester, K., Bodenschatz, E., Herminghaus, S., Sourjik, V., Erb, T., Bastiaens, P., Lipowsky, R., Hyman, A., Dabrock, P., Baret, J. P., Vidaković-Koch, T., Bieling, P., Dimova, R., Mutschler, H., Robinson, T., Tang, D., Wegner, S., & Sundmacher, K. (2018). MaxSynBio - Avenues towards creating cells from the bottom up. Angewandte Chemie International Edition, 57(41), 13382-13392. doi:10.1002/anie.201802288.


引用: https://hdl.handle.net/21.11116/0000-0001-64C1-4
要旨
A large Max Planck‐based German research consortium ('MaxSynBio') was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom‐up approach to Synthetic Biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life, via their modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non‐living components. The fundamental insights gained from the activities in MaxSynBio can eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace natural cells currently used in conventional biotechnology.