Decreased Cerebral Blood Volume and Flow in Areas with Negative BOLD Indicates 
the Mechanism for Negative BOLD May Be Stimulus- and Area-Specific

Goense, J; Bohraus, Y; Logothetis, NK

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Decreased Cerebral Blood Volume and Flow in Areas with Negative BOLD Indicates the Mechanism for Negative BOLD May Be Stimulus- and Area-Specific

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Goense, J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Bohraus, Y
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Logothetis, NK
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Goense, J., Bohraus, Y., & Logothetis, N. (2013). Decreased Cerebral Blood Volume and Flow in Areas with Negative BOLD Indicates the Mechanism for Negative BOLD May Be Stimulus- and Area-Specific. Poster presented at 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT, USA.

引用: https://hdl.handle.net/21.11116/0000-0001-4E7B-F

要旨

In earlier work, we showed increased CBV in regions with negative BOLD responses. This seems to disagree with work in cats where CBV was decreased in areas with negative BOLD. Here, we used a full-field checkerboard stimulus and show decreased CBV and CBF in areas that show negative BOLD responses. However, this type of negative BOLD signals occurred in peripheral V1 and extrastriate visual cortex. Our results suggest that different mechanisms for negative BOLD exist and that these may be area-dependent.