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T2-weighted BOLD fMRI at 9.4 T using a S2-SSFP-EPI sequence

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Ehses,  P
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Budde,  J
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Shajan,  G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  K
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Ehses, P., Budde, J., Shajan, G., & Scheffler, K. (2013). T2-weighted BOLD fMRI at 9.4 T using a S2-SSFP-EPI sequence. In 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013).


Cite as: http://hdl.handle.net/21.11116/0000-0001-4F50-D
Abstract
It has been hypothesized that T2-weighted BOLD fMRI at ultra-high field shows higher spatial specificity than T2*-weighted BOLD, since the main signal contribution is expected to come from the extravascular spins of the microvasculature. Unfortunately, the number of slices that can be acquired in multi-slice SE-EPI is limited at ultra-high field due to SAR constraints. T2-weighted steady-state sequences, such as S2-SSFP, have been previously used as an alternative to spin-echo based BOLD fMRI. In this work, we present a 3D S2-SSFP sequence that is accelerated using an EPI readout and show first results from finger tapping experiments at 9.4 T.