Metabolite-Cycled, ECG-Triggered and Navigator-Gated 1H MRS with Optimised 
Image-Based B0 Shimming Achieves High Spectral Quality in the Myocardium at 3T,

Cameron, D; Fillmer, A; Hock, A; Redpath, TW; Frenneaux, MP; Dawson, D; Henning, A

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Metabolite-Cycled, ECG-Triggered and Navigator-Gated 1H MRS with Optimised Image-Based B0 Shimming Achieves High Spectral Quality in the Myocardium at 3T,

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Henning, A
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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https://www.ismrm.org/13/tp01.htm
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Zitation

Cameron, D., Fillmer, A., Hock, A., Redpath, T., Frenneaux, M., Dawson, D., et al. (2013). Metabolite-Cycled, ECG-Triggered and Navigator-Gated 1H MRS with Optimised Image-Based B0 Shimming Achieves High Spectral Quality in the Myocardium at 3T,. Poster presented at 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT, USA.

Zitierlink: https://hdl.handle.net/21.11116/0000-0001-5725-4

Zusammenfassung

Cardiac 1H MRS can be used assess myocardial lipid content and to investigate pathophysiologies, but spectral quality is severely limited by cardiac and respiratory motion, as well as static field inhomogeneities, which are especially challenging at higher field strengths. In this work, ECG-triggering, navigator-gating, frequency alignment and phase correction are combined, for the first time, with a metabolite-cycled 1H cardiac MRS method and an improved ‘Localised B0 Shimming Tool’ to produce superlative motion compensation at 3T. Resulting spectra, acquired in 5 volunteers, show superior quality to others reported at this field strength (e.g. CH2 lipid SNR=28, FWHM=25, CRLB=1.8%).