English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Micromotors powered by enzyme catalysis

MPS-Authors
/persons/resource/persons219873

Golestanian,  R.
Department of Living Matter Physics, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

External Ressource
No external resources are shared
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Dey, K. K., Zhao, X., Tansi, B. M., Méndez-Ortiz, J. W., Córdova-Figueroa, U. M., Golestanian, R., et al. (2015). Micromotors powered by enzyme catalysis. Nano Letters, 15(12), 8311-8315. doi:10.1021/acs.nanolett.5b03935.


Cite as: http://hdl.handle.net/21.11116/0000-0001-A796-9
Abstract
Active biocompatible systems are of great current interest for their possible applications in drug or antidote delivery at specific locations. Herein, we report the synthesis and study of self-propelled microparticles powered by enzymatic reactions and their directed movement in substrate concentration gradient. Polystyrene microparticles were functionalized with the enzymes urease and catalase using a biotin-streptavidin linkage procedure. The motion of the enzyme-coated particles was studied in the presence of the respective substrates, using optical microscopy and dynamic light scattering analysis. The diffusion of the particles was found to increase in a substrate concentration dependent manner. The directed chemotactic movement of these enzyme-powered motors up the substrate gradient was studied using three-inlet microfluidic channel architecture. © 2015 American Chemical Society.