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Multiline balanced SSFP for rapid functional imaging at ultrahigh field

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Ehses,  P
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  K
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Ehses, P., & Scheffler, K. (2018). Multiline balanced SSFP for rapid functional imaging at ultrahigh field. Magnetic Resonance in Medicine, 79(2), 994-1000. doi:10.1002/mrm.26761.


Cite as: http://hdl.handle.net/21.11116/0000-0001-7D12-F
Abstract
Purpose The goal of this study is to develop and evaluate a multiline balanced steady-state free-precession (bSSFP) sequence for passband functional MRI at ultrahigh field. Methods Passband bSSFP functional MRI experiments using a visual task were performed on a 9.4 T system with echo trains ranging from one up to seven echoes. We analyze the acquisition efficiency, temporal and thermal signal-to-noise ratio, as well as the observed blood oxygen–level-dependent (BOLD) signal changes. Results With increasing repetition time and echo train length, the BOLD-related signal change as well as the thermal and temporal noise were improved. Activation patterns and signal changes were stable and reproducible across subjects. Conclusions We propose a multiline bSSFP for functional BOLD imaging that approaches the speed of echo-planar imaging and that shows an increased BOLD sensitivity compared with single-line bSSFP.