Single-shot whole-brain CEST imaging using centric-reordered 3D-EPI

Akbey, S; Ehses, P; Stirnberg, R; Zaiss, M; Stöcker, T

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Single-shot whole-brain CEST imaging using centric-reordered 3D-EPI

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Zaiss, M
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Akbey, S., Ehses, P., Stirnberg, R., Zaiss, M., & Stöcker, T. (2018). Single-shot whole-brain CEST imaging using centric-reordered 3D-EPI. Poster presented at Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.

Cite as: https://hdl.handle.net/21.11116/0000-0001-7D8A-8

Abstract

We present a 3D CEST sequence that allows 2mm isotropic whole-brain acquisition within 6s per frequency offset. The 4.5s CEST preparation is followed by a 1.5s centric-reordered 3D-EPI readout with water excitation. The single-shot readout improves robustness against physiological noise and provides complete freedom in the design of the saturation block. We acquired whole-brain CEST data at 7T and show metabolite maps obtained from a Lorentzian fit to the Z-spectra.