Estimation of T2 Relaxation Times of Downfield Peaks in Human Brain at 9.4 T

Murali Manohar, SV; Borbath, T; Fichtner, N; Giapitzakis, IA; Zaldivar, D; Kreis, R; Henning, A

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Estimation of T2 Relaxation Times of Downfield Peaks in Human Brain at 9.4 T

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Murali Manohar, SV
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Borbath, T
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Giapitzakis, IA
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Zaldivar, D
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Henning, A
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Murali Manohar, S., Borbath, T., Fichtner, N., Giapitzakis, I., Zaldivar, D., Kreis, R., & Henning, A. (2018). Estimation of T2 Relaxation Times of Downfield Peaks in Human Brain at 9.4 T. Poster presented at Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.

引用: https://hdl.handle.net/21.11116/0000-0001-7DC0-A

要旨

T2 relaxations times for the downfield metabolites in human brain 1H MR spectra were estimated at 9.4 T. A possible new peak at 8.35 ppm with rapid T2 decay is reported. Due to the use of a non-water suppressed MRS method, the T2 of slowly exchanging peaks could be assessed. The shorter T2 relaxation times in the downfield compared to the upfield spectral areas leads us to suspect a macromolecular contribution, while also exchange effects may contribute to the short apparent T2s.