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Validation of tractography against in vivo tracing in the macaque visual system: effect of distance correction

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Augath,  M
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Logothetis,  NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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引用

Azadbakht, H., Parkes, L., Haroon, H., Augath, M., Logothetis, N., de Crespigny, A., D’Arceuil, H., & Parker, G. (2012). Validation of tractography against in vivo tracing in the macaque visual system: effect of distance correction. Poster presented at 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia.


引用: http://hdl.handle.net/21.11116/0000-0001-A535-9
要旨
Validation of diffusion imaging has proved difficult due to the lack of an adequate gold-standard. In this work, the macaque visual system is used as a model, in which due to an extensive literature of in-vivo and post-mortem tracer studies, true connections are well-established. We performed probabilistic tractography on diffusion imaging data from two in-vitro macaque brains, and comparisons were made between identified connections at different thresholds of connection strength, and connections identified in the visual system wiring map of Felleman & van Essen. The effects of streamline-length based correction of the distance bias of probabilistic tractography were also explored.