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Journal Article

H2O2 yield of atmospherically relevant quinones in surrogate lung fluid

MPS-Authors
/persons/resource/persons204194

Filippi,  Alexander
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons222961

Li,  Chenpei
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons222959

Lelieveld,  Steven
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons187669

Lucas,  Kurt
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons101189

Pöschl,  Ulrich
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons192191

Tong,  Haijie
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

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Citation

Filippi, A., Li, C., Lelieveld, S., Lucas, K., Wang, Y., Pöschl, U., et al. (2018). H2O2 yield of atmospherically relevant quinones in surrogate lung fluid. Free Radical Biology and Medicine, 120(Suppl. 1), S105-S105. doi:10.1016/j.freeradbiomed.2018.04.346.


Cite as: https://hdl.handle.net/21.11116/0000-0001-AA15-8
Abstract
Inhalation of fine particulate matter can lead to the formation of ra- dicals and H 2 O 2 in epithelial lung fluid (ELF), induce oxidative stress and cause adverse health effects. 1,2 Quinones are important redox-active components of fine particulate matter that may be essential for the generation of H 2 O 2 and oxidative stress. We investigated the H 2 O 2 yield of 9,10 anthraquinone, 1,2- and 1,4- naphthoquinones in surrogate lung fluid (SLF). We found that 9,10 anthraquinone has a relatively low H 2 O 2 yield in SLF, whereas 1,2- and 1,4- naphthoquinone exhibit high and strongly pH- dependent H 2 O 2 yields. E-mail address: a.filippi@mpic.de References 1:Pope III and Dockery, Journal of the air and waste management as- sociation 2006, 56, (6), 709–742. 2:Lakey, et al., Scientific reports 2016, 6, 3291