In situ detection of cells and biochemical reactions by optical diffraction

Morhard, F.; Dahint, R.; Grunze, M.

doi:10.1007/978-94-011-5286-0_111

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In situ detection of cells and biochemical reactions by optical diffraction

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Grunze, M.
Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society;

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Citation

Morhard, F., Dahint, R., & Grunze, M. (1998). In situ detection of cells and biochemical reactions by optical diffraction. In D. J. Harrison, & A. Berg (Eds.), Micro Total Analysis Systems ’98: Proceedings of the uTAS ’98 Workshop, held in Banff, Canada, 13–16 October 1998 (pp. 469-472). Dordrecht: Kluwer Academic Publishers.

Cite as: https://hdl.handle.net/21.11116/0000-0001-B77F-3

Abstract

The combination of mesoscopic surface patterning and Fourier diffraction optics represents a new sensor concept for (bio)chemical applications. Antibodies have been covalently linked to microstructures formed by μCP and provide the basis for the in situ detection of cells, which serve as scattering elements for the incident laser beam.