Deutsch
 
Benutzerhandbuch Datenschutzhinweis Impressum Kontakt
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT

Freigegeben

Zeitschriftenartikel

Organ Function as a Modulator of Organ Formation: Lessons from Zebrafish

MPG-Autoren
/persons/resource/persons224227

Collins,  Michelle M.
Developmental Genetics, Max Planck Institute for Heart and Lung Research, Max Planck Society;

/persons/resource/persons224278

Stainier,  Didier Y.R.
Developmental Genetics, Max Planck Institute for Heart and Lung Research, Max Planck Society;

Externe Ressourcen
Es sind keine Externen Ressourcen verfügbar
Volltexte (frei zugänglich)
Es sind keine frei zugänglichen Volltexte verfügbar
Ergänzendes Material (frei zugänglich)
Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar
Zitation

Collins, M. M., & Stainier, D. Y. (2016). Organ Function as a Modulator of Organ Formation: Lessons from Zebrafish. ESSAYS ON DEVELOPMENTAL BIOLOGY, PT B, 417-433. doi:10.1016/bs.ctdb.2015.10.017.


Zitierlink: http://hdl.handle.net/21.11116/0000-0001-BF22-2
Zusammenfassung
Organogenesis requires an intricate balance between cell differentiation and tissue growth to generate a complex and fully functional organ. However, organogenesis is not solely driven by genetic inputs, as the development of several organ systems requires their own functionality. This theme is particularly evident in the developing heart as progression of cardiac development is accompanied by increased and altered hemodynamic forces. In the absence or disruption of these forces, heart development is abnormal, suggesting that the heart must sense these changes and respond appropriately. Here, we discuss concepts of how embryonic heart function contributes to heart development using lessons learned mostly from studies in zebrafish.