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Are branched chain fatty acids the natural substrates for P450(BM3)?

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Cryle,  Max
Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society;

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Citation

Cryle, M., Espinoza, R. D., Smith, S. J., Matovic, N. J., & De Voss, J. J. (2006). Are branched chain fatty acids the natural substrates for P450(BM3)? Chemical Communications, 22, 2353-2355. doi:10.1039/b601202g.


Cite as: https://hdl.handle.net/21.11116/0000-0001-E75C-4
Abstract
Branched chain fatty acids are substrates for cytochrome P450(BM3) (CYP102) from Bacillus megaterium; oxidation of C15 and C17 iso and anteiso fatty acids by P450(BM3) leads to the formation of hydroxylated products that possess high levels of regiochemical and stereochemical purity.