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Arabidopsis BTB/POZ protein-dependent PENETRATION3 trafficking and disease susceptibility

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Hagmann,  J
Department Molecular Biology, Max Planck Institute for Developmental Biology, Max Planck Society;

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引用

Mao, H., Aryal, B., Langenecker, T., Hagmann, J., Geisler, M., & Grebe, M. (2017). Arabidopsis BTB/POZ protein-dependent PENETRATION3 trafficking and disease susceptibility. Nature Plants, 3(11), 854-858. doi:10.1038/s41477-017-0039-z.


引用: https://hdl.handle.net/21.11116/0000-0002-04D8-6
要旨
The outermost cell layer of plant roots (epidermis) constantly encounters environmental challenges. The epidermal outer plasma membrane domain harbours the PENETRATION3 (PEN3)/ABCG36/PDR8 ATP-binding cassette transporter that confers non-host resistance to several pathogens. Here, we show that the Arabidopsis ENDOPLASMIC RETICULUM-ARRESTED PEN3 (EAP3) BTB/POZ-domain protein specifically mediates PEN3 exit from the endoplasmic reticulum and confers resistance to a root-penetrating fungus, providing prime evidence for BTB/POZ-domain protein-dependent membrane trafficking underlying disease resistance.