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A multi-center study on fast full-brain quantitative multi-parameter mapping of R1, MT, and R2*: Scan-rescan repeatability and inter-site reproducibility

MPS-Authors

Seif,  Maryam
External Organizations;
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Leutritz,  Tobias
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Freund,  Patrick
External Organizations;
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Weiskopf,  Nikolaus
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Citation

Seif, M., Leutritz, T., Samson, R. S., Curt, A., Wheeler-Kingshott, C. A. G., Freund, P., et al. (2018). A multi-center study on fast full-brain quantitative multi-parameter mapping of R1, MT, and R2*: Scan-rescan repeatability and inter-site reproducibility. In Proceedings of the 2018 Annual Meeting of the International Society for Magnetic Resonance in Medicine.


Cite as: https://hdl.handle.net/21.11116/0000-0002-12FD-D
Abstract
We present a multi-center, multi-vendor study evaluating repeatability and reproducibility of quantitative MRI data acquired using high resolution (1 mm³) multi-parameter mapping (MPM) which provides quantitative R1, MT and R2* maps of the whole brain within less than 18 min. The protocol was implemented at four clinical sites with different Siemens and Philips 3T MRI scanners. Scan-rescan measurement of the same five healthy volunteers at all sites showed good intra-site reproducibility in all parameter maps. However, tThe inter-site comparisons showed a higher reproducibility on Siemens scanner. than on the Philips scanner.