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Journal Article

Nuclear envelope dynamics in oocytes: From germinal vesicle breakdown to mitosis.

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Lenart,  P.
Research Group of Cytoskeletal Dynamics in Oocytes, MPI for Biophysical Chemistry, Max Planck Society;

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Citation

Lenart, P., & Ellenberg, J. (2003). Nuclear envelope dynamics in oocytes: From germinal vesicle breakdown to mitosis. Current Opinion in Cell Biology, 15(1), 88-95. doi:10.1016/S0955-0674(02)00011-X.


Cite as: http://hdl.handle.net/21.11116/0000-0002-126D-0
Abstract
We have recently gained new insight into the mechanisms involved in nuclear envelope breakdown, the irreversible step that commits a cell to the M phase. Results from mammalian cell and starfish oocyte studies suggest that mechanical forces of the cytoskeleton, as well as biochemical disassembly of nuclear envelope protein complexes, play important roles in this process.