chainCleaner improves genome alignment specificity and sensitivity.

Suarez, Hernando; Langer, Björn; Ladde, Pradnya; Hiller, Michael

doi:10.1093/bioinformatics/btx024

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chainCleaner improves genome alignment specificity and sensitivity.

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https://publications.mpi-cbg.de/Suarez_2017_6740.pdf
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Suarez, H., Langer, B., Ladde, P., & Hiller, M. (2017). chainCleaner improves genome alignment specificity and sensitivity. Bioinformatics (Oxford, England), 33(11), 1596-1603. doi:10.1093/bioinformatics/btx024.

Cite as: https://hdl.handle.net/21.11116/0000-0002-8BAA-2

Abstract

Accurate alignments between entire genomes are crucial for comparative genomics. However, computing sensitive and accurate genome alignments is a challenging problem, complicated by genomic rearrangements.