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Analysis of Magnetization Transfer Ratio Measurements at 3T using Multiple-Acquisition Balanced SSFP

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Gloor, M., Scheffler, K., & Bieri, O. (2011). Analysis of Magnetization Transfer Ratio Measurements at 3T using Multiple-Acquisition Balanced SSFP. In 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011).


Cite as: https://hdl.handle.net/21.11116/0000-0002-4EF4-4
Abstract
Recently, it has been shown that fast magnetization transfer (MT) scans based on balanced steady-state free precession (bSSFP) with RF pulse modification achieve high SNR and high reproducibility at 1.5T. At 3T, combination of multiple, phase-cycled, bSSFP scans might be required to overcome limitations from off-resonance artifacts. In this study, different recombination methods for the generation of accurate magnetization transfer ratio (MTR) maps were analyzed. Maximum intensity projection removes off-resonance artifacts without significant MTR modification, whereas sum-of-squares and weighted-combination bSSFP yield reduced MTR values.