Colloidal micro- and nano-particles as templates for polyelectrolyte multilayer 
capsules.

Parakhonskiy, B.; Yashchenok, A. M.; Konrad, M.; Skirtach, Andre G.

doi:10.1016/j.cis.2014.01.022

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Colloidal micro- and nano-particles as templates for polyelectrolyte multilayer capsules.

MPS-Authors

/persons/resource/persons121879

Skirtach, Andre G.
Max Planck Institute of Colloids and Interfaces, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Parakhonskiy, B., Yashchenok, A. M., Konrad, M., & Skirtach, A. G. (2014). Colloidal micro- and nano-particles as templates for polyelectrolyte multilayer capsules. Advances in Colloid and Interface Science, 207, 253-264. doi:10.1016/j.cis.2014.01.022.

Cite as: https://hdl.handle.net/21.11116/0000-0002-8031-5

Abstract

Colloidal particles play an important role in various areas of material and pharmaceutical sciences, biotechnology, and biomedicine. In this overview we describe micro- and nano-particles used for the preparation of polyelectrolyte multilayer capsules and as drug delivery vehicles. An essential feature of polyelectrolyte multilayer capsule preparations is the ability to adsorb polymeric layers onto colloidal particles or templates followed by dissolution of these templates. The choice of the template is determined by various physico-chemical conditions: solvent needed for dissolution, porosity, aggregation tendency, as well as release of materials from capsules. Historically, the first templates were based on melamine formaldehyde, later evolving towards more elaborate materials such as silica and calcium carbonate. Their advantages and disadvantages are discussed here in comparison to non-particulate templates such as red blood cells. Further steps in this area include development of anisotropic particles, which themselves can serve as delivery carriers. We provide insights into application of particles as drug delivery carriers in comparison to microcapsules templated on them.