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Conference Paper

Follow the light - From low-energy defibrillation to multi-site photostimulation

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Diaz-Rodriguez,  Laura
Research Group Biomedical Physics, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

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Luther,  Stefan
Research Group Biomedical Physics, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

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Richter,  Claudia
Research Group Biomedical Physics, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

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Citation

Diaz-Rodriguez, L., Schwaerzle, M., Ruther, P., Luther, S., & Richter, C. (2018). Follow the light - From low-energy defibrillation to multi-site photostimulation. In 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (pp. 4832-4835). Piscataway, NJ: IEEE. doi:10.1109/EMBC.2018.8513124.


Cite as: https://hdl.handle.net/21.11116/0000-0002-816A-5
Abstract
One major cause of death in the industrialized world is sudden cardiac death, which so far can be reliably treated only by applying strong electrical shocks. Developing improved methods, aiming at lowering shock intensity and associated side effects potentially has significant clinical implications. Thus, optogenetic stimulation using structured illumination has been introduced as a promising experimental tool to investigate mechanisms underlying multi-site pacing and to optimize potential low-energy approaches. Furthermore, an objective of this work is to strengthen the application of optogenetic tools for cardiac arrhythmia research, which in turn is expected to improve applicable technologies towards tissue-protective defibrillation.