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Journal Article

The impact of structural biology on alkaloid biosynthesis research

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Panjikar, S., Stoeckigt, J., O'Connor, S. E., & Warzecha, H. (2012). The impact of structural biology on alkaloid biosynthesis research. Natural Product Reports, 29(10), 1176-1200. doi:10.1039/c2np20057k.


Cite as: http://hdl.handle.net/21.11116/0000-0002-B236-8
Abstract
In the recent past, macromolecular crystallography has gone through substantial methodological and technological development. The purpose of this review is to provide a general overview of structural biology and its impact on enzyme structure/function analysis and illustrate how it is modifying the focus of research relevant to alkaloid biosynthesis.