ERETIC-Based Glycogen Quantification Using SNR-Enhanced and Localized 13C MRS

Chen, X; Henning, A; Pavan, M; Heinzer-Schweizer , S; Toigo, M; Boesiger, P

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Poster

ERETIC-Based Glycogen Quantification Using SNR-Enhanced and Localized 13C MRS

MPS-Authors

There are no MPG-Authors in the publication available

External Resource

https://cds.ismrm.org/protected/10MProceedings/files/1_program.htm
(Abstract)

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Chen, X., Henning, A., Pavan, M., Heinzer-Schweizer, S., Toigo, M., & Boesiger, P. (2010). ERETIC-Based Glycogen Quantification Using SNR-Enhanced and Localized 13C MRS. Poster presented at ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden.

Cite as: https://hdl.handle.net/21.11116/0000-0002-A50C-7

Abstract

13C MRS glycogen was detected by combined ISIS-localized NOE and proton decoupling in human calf muscle, with the ERETIC signal as a synthetic reference standard for quantification. Reproducibility tests were performed regarding the quantified signal intensities, SNR enhancement factors and ERETIC signal stability. In conclusion, the combination of NOE and decoupling can enhance the glycogen signal at a reproducible level and enables higher fitting and thus quantification reliability. As ERETIC signal stability proved to be unaffected by SNT enhancement, it is promising to use the ERETIC signal as reference for absolute quantification among different subjects and experiments.