English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse
  1. View item / 
  2. Item Summary

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Journal Article

Immediate neurophysiological effects of transcranial electrical stimulation

MPS-Authors
/persons/resource/persons187736

Melloni,  Lucia
Department of Neuroscience, Max Planck Institute for Empirical Aesthetics, Max Planck Society;
New York University Comprehensive Epilepsy Center;
Department of Neurology, NYU Langone Health;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)

s41467-018-07233-7.pdf
(Publisher version), 2MB

Supplementary Material (public)
There is no public supplementary material available
Citation

Liu, A., Vöröslakos, M., Kronberg, G., Henin, S., Krause, M. R., Huang, Y., et al. (2018). Immediate neurophysiological effects of transcranial electrical stimulation. Nature Communications, 9: 5092. doi:10.1038/s41467-018-07233-7.


Cite as: https://hdl.handle.net/21.11116/0000-0002-B8D8-B
Abstract
Noninvasive brain stimulation techniques are used in experimental and clinical fields for their potential effects on brain network dynamics and behavior. Transcranial electrical stimulation (TES), including transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), has gained popularity because of its convenience and potential as a chronic therapy. However, a mechanistic understanding of TES has lagged behind its widespread adoption. Here, we review data and modelling on the immediate neurophysiological effects of TES in vitro as well as in vivo in both humans and other animals. While it remains unclear how typical TES protocols affect neural activity, we propose that validated models of current flow should inform study design and artifacts should be carefully excluded during signal recording and analysis. Potential indirect effects of TES (e.g., peripheral stimulation) should be investigated in more detail and further explored in experimental designs. We also consider how novel technologies may stimulate the next generation of TES experiments and devices, thus enhancing validity, specificity, and reproducibility.