BReDi mouse: A novel transgenic mouse strain to track and deplete B cells.

Mues, Marsilius; Krishnamoorthy, Gurumoorthy

doi:10.1002/eji.201847930

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BReDi mouse: A novel transgenic mouse strain to track and deplete B cells.

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Mues, Marsilius
Emeritus Group: Neuroimmunology / Wekerle, MPI of Neurobiology, Max Planck Society;

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Krishnamoorthy, Gurumoorthy
Krishnamoorthy, Gurumoorthy / Neuroinflammation and Mucosal Immunology, Max Planck Institute of Biochemistry, Max Planck Society;

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Mues, M., & Krishnamoorthy, G. (2019). BReDi mouse: A novel transgenic mouse strain to track and deplete B cells. European Journal of Immunology, 49(3), 500-503. doi:10.1002/eji.201847930.

Cite as: https://hdl.handle.net/21.11116/0000-0002-CD38-9

Abstract

BReDi mice express a red fluorescent protein together with the diphtheria toxin receptor selectively in Bcells. Bcells can be effectively visualized by red fluorescence and can be efficiently depleted in a highly controlled fashion to study their functional capacity in vivo. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.