Ion binding properties in acetonitrile of cyclo‐peptides built u from proline 
and glycine residues

Hollosi, Miklos; Wieland, Theodor

doi:10.1111/j.1399-3011.1977.tb02805.x

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Ion binding properties in acetonitrile of cyclo‐peptides built u from proline and glycine residues

MPS-Authors

/persons/resource/persons197838

Wieland, Theodor
Max Planck Institute for Medical Research, Max Planck Society;

External Resource

https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1399-3011.1977.tb02805.x
(Any fulltext)

https://doi.org/10.1111/j.1399-3011.1977.tb02805.x
(Any fulltext)

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Hollosi, M., & Wieland, T. (1977). Ion binding properties in acetonitrile of cyclo‐peptides built u from proline and glycine residues. International Journal Peptide Protein Research, 10(5), 329-341. doi:10.1111/j.1399-3011.1977.tb02805.x.

Cite as: https://hdl.handle.net/21.11116/0000-0002-CA23-3

Abstract

Ion binding properties of antamanide‐like cyclopeptides cyclo‐(Pro2–Glyn‐Pro2–Glym) (n, m = 1–3) have been studied by CD spectroscopy and by conductivity measurements. Cyclo‐(Pro2–Gly‐Pro2–Gly) forming complexes of different stoichiometry can be characterized by a strong preference of selectivity for Mg++ and Ca++ ions over alkali ions whereas the other members of the series bind selectively alkali and alkaline earth cations with ion radius of about 1 Å. Three main types of CD spectra of cyclic peptides and their complexes can be differentiated. Type I showing two negative Cotton effects at around 220 nm and 200 nm (Ib, Fig. 3), type II showing a positive band around 220 nm and a strong negative one below 190 nm (e.g. Ic in acetonitrile, Fig. 4), and type III showing a strong negative band in the 205 nm region (e.g. metal complexes of Id, Fig. 6).