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Kiss to Cross ! Non-Invasive Mapping of Cerebellar Dentate Nucleus Projections to the Cerebral Cortex

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Kumar, V., Erb, M., Pathak, S., & Grodd, W. (2009). Kiss to Cross! Non-Invasive Mapping of Cerebellar Dentate Nucleus Projections to the Cerebral Cortex. Poster presented at 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009), Honolulu, HI, USA.

Cite as: https://hdl.handle.net/21.11116/0000-0003-17B3-9
Post-mortem connectivity based methods demonstrate that the cerebellar dentate nuclei act as the main center of communication to the cerebral cortex. Dentate nuclei have a contralateral connection with the cerebral cortex. However, direct invivo diffusion imaging of this crossing and of the dentate projections to the cortex via crossing is lacking. diffusion-tractography with integration of resting-state-fMRI is used to investigate the dentate-thalamocortical circuit. The results inflect the dentate nuclei connectivity with the contralateral cortical regions via the thalamic nuclei i.e. motor, posterior-parietal, frontal, and temporal regions. In the study, connectivity based organization about the output-channels within the dentate is introduced. The study holds promise for clinical applications.