アイテム詳細

要旨

Amnesia is most closely associated with two networks, a medial temporal cortical and a medial diencephalic one (Markowitsch, in press, b). Both of these networks are interconnected and there is a still ongoing discussion whether they in fact are separable or constitute one network only (Squire, Knowlton, and Musen 1993; Aggleton and Brown, in press). To make the situation even more complex, a third memory-related network—the basal forebrain region—was introduced about two decades ago (Talland, Sweet, and Ballantine 1967; Gade 1982; Alexander and Freedman 1984; Damasio et al. 1985; Salazar et al. 1986). To add to this complexity, this third regional complex again is highly interconnected with the other two (Mesulam et al. 1983; Nieuwenhuys 1996). As an example, fornix fibers bidirectionally interconnect the basal forebrain and the medial temporal lobe system and major portions of the fornix project from the medial temporal lobe system into the medial diencephalic system (mammillary bodies).