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Mapping the neuro-glio-vascular interactions with multi-modal fMRI

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Yu,  X
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Yu, X. (2019). Mapping the neuro-glio-vascular interactions with multi-modal fMRI. Talk presented at INT Symposium on "Advanced Photonic Imaging in Neuroscience" (APIN 2019). Marseille, France. 2019-07-11 - 2019-07-12.


Cite as: http://hdl.handle.net/21.11116/0000-0003-5E70-6
Abstract
We have developed high resolution single- vessel fMRI to map the hemodynamic signal from individual penetrating arterioles and venules with concurrent calcium recording based on the fiber optic GCaMP-mediated fluorescent signal detection. Here, I will deliver our work in three aspects: 1. Describe the advanced single-vessel fMRI brain mapping from animals to humans. 2. Demonstrate the simultaneous fMRI with fiber optic calcium recordings, as well as glutamate recording. 3. Specify a unique neuro-glia-vascular interaction event underlying brain state fluctuation. A multi-modal high field fMRI platform will be introduced for functional brain mapping.